a-iduronidase knochout mouse |
|
A boy with a mutation in a-L-iduronidase, which causes Hurler syndrome. Note his coarse facial features, crouched stance, thickened digits, and protuberant abdomen. | Transgenic mice with a targeted disruption of a-L-iduronidase. Progressive coarsening of face is apparent as 8-week-old mice (left) grow to become 52-week-old mice (right). |
Examinations Photographs Movies Links Home Search noJava Home |